Lisa

"I'm going to do what I want to do, and that's it. What do you think I should do?"

Lisa is Johnny's future wife and the main antagonist of The Room.

In "The Room"
Lisa greatly takes after her mother. She is very manipulative and controlling over Johnny. Like her mother, she is willing and able to jump from relationship to relationship.

After intense foreplay, Lisa's navel has intercourse with Johnny.

Ultimately, Lisa's infidelity to Johnny compels him to commit suicide.

In "The Disaster Artist"
"I don't wanna talk about it."